NAFLD/NASH pathophysiology and diagnosis - 30 minute course

In this self-paced e-learning module we will take a look at non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).

After completing this pathophysiology and diagnosis e-learning module, you should be able to:

• understand the pathological mechanisms behind NAFLD-NASH
• understand the various means for diagnosis of NAFLD-NASH as well as their advantages and disadvantages
• know what guidelines recommend with regards to screening

This module is created by course director Onno Holleboom (AmsterdamUMC, the Netherlands) and consists of the following topics:

• A multi-system disease
  >Insulin resistance
  >Lipid metabolism and lipotoxicity
  >Inflammation & macrophage activation
  >Dysbiosis
  >Genetic factors
  ● NAFLD/NASH symptoms and signs
  ● Diagnosis
  > liver biopsy
  > Non-invasive methods
  o Biomarkers
  o NAFLD Fibrosis Score
  o Enhanced liver fibrosis (ELF) test
  o Elastography (VCTE, FibroScan, MRE)
  o Fibrosis-4 (FIB-4) test

● Screening:
> Who?
> When?
> By whom?
> Barriers to screening

Enjoyed this course? After completing the course you can sign up for updates on the upcoming educational content.